THYROGLOBULIN-ELEVATION NEGATIVE IODINE SCINTIGRAPHY (TENIS) SYNDROME IN DIFFERENTIATED THYROID CARCINOMA: A RARE ENTITY

Authors

  • Deependra Kasaudhan Ganesh Man Singh Memorial Academy of ENT and Head & Neck Studies, TU Teaching Hospital, Kathmandu, Nepal
  • Prashant Tripathi Ganesh Man Singh Memorial Academy of ENT and Head & Neck Studies, TU Teaching Hospital Kathmandu, Nepal
  • Kunjan Acharya Ganesh Man Singh Memorial Academy of ENT and Head & Neck Studies, TU Teaching Hospital, Kathmandu, Nepal

Abstract

Differentiated thyroid cancer (DTC) patients with Thyroglobulin Elevation but Negative Iodine Scintigraphy, the ‘TENIS’ syndrome, represent a diagnostic and therapeutic challenge. Routine follow up of patients with DTC after operation is usually done with serum TSH and thyroglobulin levels (Tg). Elevated thyroglobulin levels alarms a need for search for metastatic foci or remnant disease which are sometimes missed with radioiodine thyroid scan in cases of radioiodine non-avid thyroid cancers. 18 Fluoro-2-deoxyglucose Positron Emission Tomography (18FDG-PET) scan is a useful alternative to trace the metastatic foci of tumor or nodal deposits in such cases. Management, thus, can be tailored accordingly. If isolated metastatic foci is traced, it has to be resected prior to radioiodine ablation with a follow up scan and Tg determination.

Keywords: 18 FDG-PET scan, Differentiated thyroid cancer(DTC), TENIS syndrom

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Published

2017-01-02

How to Cite

1.
Kasaudhan D, Tripathi P, Acharya K. THYROGLOBULIN-ELEVATION NEGATIVE IODINE SCINTIGRAPHY (TENIS) SYNDROME IN DIFFERENTIATED THYROID CARCINOMA: A RARE ENTITY. Nepalese J ENT Head Neck Surg [Internet]. 2017 Jan. 2 [cited 2024 Jul. 6];7(2):20-2. Available from: https://njehns.org.np/index.php/njehns/article/view/171

Issue

Vol. 7 No. 2 (2016)

Section

Case Reports

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Copyright (c) 2017 Nepalese Journal of ENT Head & Neck Surgery

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This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

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